Author: Welsh, Raymond M; Bahl, Kapil; Wang, Xiaoting Z
Title: Apoptosis and loss of virus-specific CD8(+) T-cell memory Cord-id: 223cqz02 Document date: 2004_4_10
ID: 223cqz02
Snippet: CD8(+) T-cell memory to viruses is stable in the absence but volatile in the presence of other infections. Apoptotic events that occur early in acute infections delete pre-existing memory T cells, leaving the host with reduced memory (except for cross-reactive responses) to previously encountered viruses. Apoptotic events also silence the acute immune response, leaving the host with a residual population of memory T cells. Persistent infections can induce apoptotic deletions of memory T cells th
Document: CD8(+) T-cell memory to viruses is stable in the absence but volatile in the presence of other infections. Apoptotic events that occur early in acute infections delete pre-existing memory T cells, leaving the host with reduced memory (except for cross-reactive responses) to previously encountered viruses. Apoptotic events also silence the acute immune response, leaving the host with a residual population of memory T cells. Persistent infections can induce apoptotic deletions of memory T cells that are specific to the persisting virus and to previously encountered pathogens.
Search related documents:
Co phrase search for related documents- activation induce and adoptive transfer: 1, 2
- activation induce and loss apoptosis: 1
- active model and acute infection: 1
- acute infection and adoptive transfer: 1, 2, 3, 4, 5, 6
- acute infection and loss apoptosis: 1, 2
Co phrase search for related documents, hyperlinks ordered by date