Selected article for: "positive sample and real time pcr"
Author: Peters, Rebecca Marie; Schnee, Sarah Valerie; Tabatabai, Julia; Schnitzler, Paul; Pfeil, Johannes
Title: Evaluation of Alere i RSV for Rapid Detection of Respiratory Syncytial Virus in Children Hospitalized with Acute Respiratory Tract Infection
  • Cord-id: 1v56m2vq
  • Document date: 2017_3_24
    • ID: 1v56m2vq
    Snippet: Alere i RSV is a novel rapid test which applies a nicking enzyme amplification reaction to detect respiratory syncytial virus in point-of-care settings. In this study, we evaluated the Alere i RSV assay by using frozen nasopharyngeal swab samples that were collected in viral transport medium from children hospitalized with acute respiratory tract infection during the 2015-2016 winter season. Alere i RSV assay results were compared to those for Altona RealStar RSV real-time reverse transcription-
    Document: Alere i RSV is a novel rapid test which applies a nicking enzyme amplification reaction to detect respiratory syncytial virus in point-of-care settings. In this study, we evaluated the Alere i RSV assay by using frozen nasopharyngeal swab samples that were collected in viral transport medium from children hospitalized with acute respiratory tract infection during the 2015-2016 winter season. Alere i RSV assay results were compared to those for Altona RealStar RSV real-time reverse transcription-PCR (RT-PCR). We found that the overall sensitivity and specificity of the Alere i RSV test was 100% (95% confidence intervals [CI], 93% to 100%) and 97% (95% CI, 89% to 100%), respectively. Positive samples were identified within 5 to 7 min from sample collection. Overall, the Alere i RSV test performed well compared to the RT-PCR assay and has the potential to facilitate the detection of RSV in point-of-care settings.

    Search related documents:
    Co phrase search for related documents
    • acute respiratory arti tract infection and lrti tract infection: 1
    • acute respiratory arti tract infection and lung disease: 1, 2
    • acute respiratory tract infection and admission diagnosis: 1, 2
    • acute respiratory tract infection and low sensitivity: 1, 2
    • acute respiratory tract infection and lrti tract infection: 1, 2, 3, 4, 5, 6, 7, 8
    • acute respiratory tract infection and lung disease: 1, 2, 3, 4, 5, 6, 7, 8
    • acute respiratory tract infection and lyophilized test base: 1
    • acute respiratory tract infection and lyophilized test base eluate: 1
    • acute respiratory tract infection and lysis buffer: 1
    • admission diagnosis and low sensitivity: 1
    • admission diagnosis and lrti tract infection: 1
    • admission diagnosis and lung disease: 1, 2, 3
    • low sensitivity and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
    • low sensitivity and lysis buffer: 1
    • lrti tract infection and lung disease: 1, 2, 3