Selected article for: "recombinant protein and SARS CoV spike"

Author: Asif Shajahan; Nitin T. Supekar; Anne S. Gleinich; Parastoo Azadi
Title: Deducing the N- and O-glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2
  • Document date: 2020_4_3
  • ID: f0xsisdg_22
    Snippet: Two very recent preprints reporting N-glycosylation on spike protein of SARS-CoV-2 showed different glycosylation profiles, and both reports were different from our results although all three studies utilized recombinant S protein from an HEK 293-based expression system (Watanabe, Y., Allen, J.D., et al. 2020 , Zhang, Y., Zhao, W., et al. 2020 ). This indicates the caution to be exercised in determining the glycosylation on viral antigens generat.....
    Document: Two very recent preprints reporting N-glycosylation on spike protein of SARS-CoV-2 showed different glycosylation profiles, and both reports were different from our results although all three studies utilized recombinant S protein from an HEK 293-based expression system (Watanabe, Y., Allen, J.D., et al. 2020 , Zhang, Y., Zhao, W., et al. 2020 ). This indicates the caution to be exercised in determining the glycosylation on viral antigens generated from various sources as author/funder. All rights reserved. No reuse allowed without permission.

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