Selected article for: "acute respiratory and liver transplant"
Author: Alconchel, Felipe; Cascales-Campos, Pedro A; Pons, Jose A; Martínez, María; Valiente-Campos, Josefa; Gajownik, Urszula; Ortiz, María L; Martínez-Alarcón, Laura; Parrilla, Pascual; Robles, Ricardo; Sánchez-Bueno, Francisco; Moreno, Santiago; Ramírez, Pablo
Title: Severe COVID-19 after liver transplantation, surviving the pitfalls of learning on-the-go: Three case reports
  • Cord-id: 142a2wnd
  • Document date: 2020_10_27
    • ID: 142a2wnd
    Snippet: BACKGROUND: The novel coronavirus 2019 (COVID-19) pandemic has dramatically transformed the care of the liver transplant patient. In patients who are immunosuppressed and with multiple comorbidities, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been associated with increased severity and mortality. The main objective of this report is to communicate our experience in the therapeutic management of SARS-CoV-2 infection in 3 liver transplant patients. Secondly, we stre
    Document: BACKGROUND: The novel coronavirus 2019 (COVID-19) pandemic has dramatically transformed the care of the liver transplant patient. In patients who are immunosuppressed and with multiple comorbidities, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been associated with increased severity and mortality. The main objective of this report is to communicate our experience in the therapeutic management of SARS-CoV-2 infection in 3 liver transplant patients. Secondly, we stress the management and investigation of the contagious spreading into a liver transplant ward. CASE SUMMARY: The patients were two women (aged 61 years and 62 years) and one man (aged 68 years), all of them having recently received a liver transplant. All three patients required intensive care unit admission and invasive mechanical ventilation. Two of them progressed severely until death. The other one, who received tocilizumab, had a good recovery. In the outbreak, the wife of one of the patients and four healthcare professionals involved in their care were also infected. CONCLUSION: We illustrate in detail the evolution of a nosocomial COVID-19 outbreak in a liver transplant ward. We believe that these findings will contribute to a better understanding of the natural history of the disease and will improve the treatment of the liver transplant patient with COVID-19.

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