Author: Chan, Paul K. S.; Ng, King-Cheung; Chan, Rickjason C. W.; Lam, Rebecca K. Y.; Chow, Viola C. Y.; Hui, Mamie; Wu, Alan; Lee, Nelson; Yap, Florence H.Y.; Cheng, Frankie W. T.; Sung, Joseph J. Y.; Tam, John S.
Title: Immunofluorescence Assay for Serologic Diagnosis of SARS Cord-id: 15rcq4sh Document date: 2004_3_25
ID: 15rcq4sh
Snippet: We evaluated a virus-infected cell-based indirect immunofluorescence assay for detecting anti–severe acute respiratory syndrome-associated coronavirus (SARS-CoV) immunoglobulin (Ig) G antibody. All confirmed SARS cases demonstrated seroconversion or fourfold rise in IgG antibody titer; no control was positive. Sensitivity and specificity of this assay were both 100%. Immunofluorescence assay can ascertain the status of SARS-CoV infection.
Document: We evaluated a virus-infected cell-based indirect immunofluorescence assay for detecting anti–severe acute respiratory syndrome-associated coronavirus (SARS-CoV) immunoglobulin (Ig) G antibody. All confirmed SARS cases demonstrated seroconversion or fourfold rise in IgG antibody titer; no control was positive. Sensitivity and specificity of this assay were both 100%. Immunofluorescence assay can ascertain the status of SARS-CoV infection.
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