Author: Yuanmei Zhu; Danwei Yu; Hongxia Yan; Huihui Chong; Yuxian He
Title: Design of potent membrane fusion inhibitors against SARS-CoV-2, an emerging coronavirus with high fusogenic activity Document date: 2020_3_28
ID: cogk5kig_1
Snippet: In late December of 2019, a new infectious respiratory disease emerged in Wuhan, China. The 34 pathogen was soon identified as a novel coronavirus (CoV) (1-3), which was initially termed comprises of S1 and S2 subunits and exists in a metastable prefusion conformation. The S1 52 subunit, which contains a receptor-binding domain (RBD) capable of functional folding 53 independently, is responsible for virus binding to the cell surface receptor. A r.....
Document: In late December of 2019, a new infectious respiratory disease emerged in Wuhan, China. The 34 pathogen was soon identified as a novel coronavirus (CoV) (1-3), which was initially termed comprises of S1 and S2 subunits and exists in a metastable prefusion conformation. The S1 52 subunit, which contains a receptor-binding domain (RBD) capable of functional folding 53 independently, is responsible for virus binding to the cell surface receptor. A recent study 54 author/funder. All rights reserved. No reuse allowed without permission.
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