Author: V’kovski Philip; Gerber Markus; Kelly Jenna; Pfaender Stephanie; Ebert Nadine; Braga Lagache Sophie; Simillion Cedric; Portmann Jasmine; Stalder Hanspeter; Gaschen Véronique; Bruggmann Remy; Stoffel Michael; Heller Manfred; Dijkman Ronald; Thiel Volker
Title: Determination of host cell proteins constituting the molecular microenvironment of coronavirus replicase complexes by proximity-labeling Document date: 2018_9_14
ID: jgrilsfc_1
Snippet: 8 peptide of only 14 amino acids at the carboxyterminus of polyprotein 1a with a yet unassigned 159 role or function in coronavirus replication, (ii) the structural proteins spike (S) protein, 160 envelope (E) protein, and membrane (M) protein, which mainly localize to sites of viral 161 assembly before being incorporated into newly-formed viral particles, and (iii) all accessory 162 proteins (NS2a, HE, ORF4, ORF5a). Altogether, these results val.....
Document: 8 peptide of only 14 amino acids at the carboxyterminus of polyprotein 1a with a yet unassigned 159 role or function in coronavirus replication, (ii) the structural proteins spike (S) protein, 160 envelope (E) protein, and membrane (M) protein, which mainly localize to sites of viral 161 assembly before being incorporated into newly-formed viral particles, and (iii) all accessory 162 proteins (NS2a, HE, ORF4, ORF5a). Altogether, these results validate the proximity-163 dependent biotinylation approach and demonstrate the specific and exclusive labeling of MHV-164 RTC-associated proteins (Fig. 2d) . 165
Search related documents:
Co phrase search for related documents- amino acid and spike structural protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22
- amino acid and structural protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77
- amino acid and viral particle: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- newly form and structural protein: 1
- spike structural protein and structural protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76
- spike structural protein and viral particle: 1
- structural protein and viral particle: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
Co phrase search for related documents, hyperlinks ordered by date