Author: Miyssa I. Abdelmageed; Abdelrahman H. Abdelmoneim; Mujahed I. Mustafa; Nafisa M. Elfadol; Naseem S. Murshed; Shaza W. Shantier; Abdelrafie M. Makhawi
Title: Design of multi epitope-based peptide vaccine against E protein of human COVID-19: An immunoinformatics approach Document date: 2020_2_11
ID: 6ojmmmuj_46
Snippet: Designing of a novel vaccine is very crucial to defending the rapid endless of global burden of disease [56] [57] [58] [59] . In the last few decades, biotechnology has advanced rapidly; alongside with the understanding of immunology which assisted the rise of new approaches towards rational vaccines design [60] . Peptide-based vaccines are designed to elicit immunity particular pathogens by selectively stimulating antigen specific for B and T ce.....
Document: Designing of a novel vaccine is very crucial to defending the rapid endless of global burden of disease [56] [57] [58] [59] . In the last few decades, biotechnology has advanced rapidly; alongside with the understanding of immunology which assisted the rise of new approaches towards rational vaccines design [60] . Peptide-based vaccines are designed to elicit immunity particular pathogens by selectively stimulating antigen specific for B and T cells [61] .Applying the advanced bioinformatics tools and databases, various peptide-based vaccines could be designed where the peptides act as ligands [62] [63] [64] . This approach has been used frequently in Saint Louis encephalitis virus [65] , dengue virus [66] , chikungunya virus [67] proposing promising peptides for designing vaccines.
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