Author: Miyssa I. Abdelmageed; Abdelrahman H. Abdelmoneim; Mujahed I. Mustafa; Nafisa M. Elfadol; Naseem S. Murshed; Shaza W. Shantier; Abdelrafie M. Makhawi
Title: Design of multi epitope-based peptide vaccine against E protein of human COVID-19: An immunoinformatics approach Document date: 2020_2_11
ID: 6ojmmmuj_54
Snippet: Although both flu and anti-HIV drugs are used currently in China for treatment of COVID-19, and chloroquine phosphate, an old drug for treatment of malaria, has recently found to have apparent efficacy and acceptable safety against 79] ; nevertheless more studies are required to standardize these therapies. In addition, there has been some success in the development of mouse models of MERS-CoV and SARS-CoV infection, and candidate vaccines where .....
Document: Although both flu and anti-HIV drugs are used currently in China for treatment of COVID-19, and chloroquine phosphate, an old drug for treatment of malaria, has recently found to have apparent efficacy and acceptable safety against 79] ; nevertheless more studies are required to standardize these therapies. In addition, there has been some success in the development of mouse models of MERS-CoV and SARS-CoV infection, and candidate vaccines where the envelope (E) protein is mutated or deleted have been described [80] [81] [82] [83] [84] [85] [86] . To best of our knowledge, this is the first study to identify certain peptides in envelope (E) protein as candidates for COVID-19. Accordingly, these epitopes were strongly recommended as promising epitopes vaccine candidate against T cell.
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