Author: Asiedu Ebenezer
Title: Designing Effective small interfering RNA for Post-Transcriptional Silencing of Human GREM1: A Comprehensive Bioinformatics Approach Document date: 2020_1_24
ID: j99qg2a0_32
Snippet: The efficacy of the selected siRNA candidates ultimately depends on availability of their target sites. The probability that a target site is available for binding was computed with the Sirna module. The algorithm provides the probability profile for single-stranded regions in the target mRNA [28] . Target sites that are accessible have high probabilities of being single stranded. The probability profiles for all the selected siRNA target sites a.....
Document: The efficacy of the selected siRNA candidates ultimately depends on availability of their target sites. The probability that a target site is available for binding was computed with the Sirna module. The algorithm provides the probability profile for single-stranded regions in the target mRNA [28] . Target sites that are accessible have high probabilities of being single stranded. The probability profiles for all the selected siRNA target sites are shown in Figure 3 .
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