Author: Tatebe, Myris Satiko Shinzato; de Barros Dorna, Mayra; Castro, Ana Paula Beltran Moschione; Pastorino, Antonio Carlos
Title: Inflammatory Manifestations in Children with Chronic Granulomatous Disease. Cord-id: 0tpfaqm7 Document date: 2021_2_22
ID: 0tpfaqm7
Snippet: Chronic granulomatous disease (CGD) is a human inborn error of immunity caused by defects in the NADPH oxidase, an enzyme complex responsible for reactive oxygen species (ROS) metabolism. It is characterized by impaired microbicidal activity of the phagocytes, predisposing patients to bacterial and fungal infections, mainly pneumonia, abscesses and adenitis 1,2 .
Document: Chronic granulomatous disease (CGD) is a human inborn error of immunity caused by defects in the NADPH oxidase, an enzyme complex responsible for reactive oxygen species (ROS) metabolism. It is characterized by impaired microbicidal activity of the phagocytes, predisposing patients to bacterial and fungal infections, mainly pneumonia, abscesses and adenitis 1,2 .
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