Author: Mendes-Correa, M. C.; Ghilardi, F.; Salomao, M. C.; Villas-Boas, L. S.; Vincente de Paula, A.; Tozetto-Mendoza, T. R.; Freire, W.; Sales, F. C. d. S.; Romano, C. M.; Claro, I. M.; de Souza, L. M.; Ramos, J. F.; Paiao, H. G. d. O.; Szor, R. S.
Title: SARS-CoV-2 shedding, infectivity and evolution in an immunocompromised adult patient Cord-id: 199hg8q9 Document date: 2021_6_15
ID: 199hg8q9
Snippet: Abstract This report describes a persistent SARS-CoV-2 infection of at least 218 days in a male, in his forties who had undergone a prior autologous hematopoietic stem cell transplant due to a diffuse large B-cell lymphoma. He did not manifest a humoral immune response to the virus. Whole-genome sequencing and viral cultures confirmed a continual infection with a replication-positive virus that had undergone genetic variation for at least 196 days following symptom onset.
Document: Abstract This report describes a persistent SARS-CoV-2 infection of at least 218 days in a male, in his forties who had undergone a prior autologous hematopoietic stem cell transplant due to a diffuse large B-cell lymphoma. He did not manifest a humoral immune response to the virus. Whole-genome sequencing and viral cultures confirmed a continual infection with a replication-positive virus that had undergone genetic variation for at least 196 days following symptom onset.
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