Selected article for: "assay sensitivity and PCR assay"
Author: Armin Ensser; Klaus Ueberla
Title: Determination of daily reproduction numbers of SARS-CoV2 based on death cases suggests more rapid initial spread in Italy and the United States
  • Document date: 2020_3_31
    • ID: 4izymiy4_25
    Snippet: Here we describe an assay for HIV-1 integration based on real-time quantitative Alu-gag PCR. This assay has sufficient sensitivity and specificity to permit its use in the study of nonproductive or latent HIV-1 infection in resting primary CD4 Ï© T cells. Reservoirs of such cells accumulate early in the course of HIV-1 infection in vivo (4, (6) (7) (8) 17) . The virus within these cells evades both antiviral immune responses and antiretroviral th.....
    Document: Here we describe an assay for HIV-1 integration based on real-time quantitative Alu-gag PCR. This assay has sufficient sensitivity and specificity to permit its use in the study of nonproductive or latent HIV-1 infection in resting primary CD4 Ï© T cells. Reservoirs of such cells accumulate early in the course of HIV-1 infection in vivo (4, (6) (7) (8) 17) . The virus within these cells evades both antiviral immune responses and antiretroviral therapy, preventing the cure of HIV disease by current medications (9, 31, 33) .

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