Selected article for: "cell epitope and world population"
Author: Miyssa I. Abdelmageed; Abdelrahman H. Abdelmoneim; Mujahed I. Mustafa; Nafisa M. Elfadol; Naseem S. Murshed; Shaza W. Shantier; Abdelrafie M. Makhawi
Title: Design of multi epitope-based peptide vaccine against E protein of human COVID-19: An immunoinformatics approach
  • Document date: 2020_2_11
    • ID: 6ojmmmuj_56
    Snippet: Extensive mutations, insertion and deletion were discovered in COVID-19 strain using the comparative sequencing. In addition, a number of MHC class I and II related peptides were found promising candidates. Among which the peptides YVYSRVKNL, SLVKPSFYV and LAILTALRL show high potentiality for vaccine design with adequate world population coverage. T cell epitope-based peptide vaccine was designed for COVID-19 using envelope protein as an immunoge.....
    Document: Extensive mutations, insertion and deletion were discovered in COVID-19 strain using the comparative sequencing. In addition, a number of MHC class I and II related peptides were found promising candidates. Among which the peptides YVYSRVKNL, SLVKPSFYV and LAILTALRL show high potentiality for vaccine design with adequate world population coverage. T cell epitope-based peptide vaccine was designed for COVID-19 using envelope protein as an immunogenic target; nevertheless, the proposed vaccine rapidly needs to be validated clinically ensuring its safety and immunogenic profile to help on stopping this epidemic before it leads to devastating global outbreaks.

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