Author: Ilda D’Annessa; Filippo Marchetti; Giorgio Colombo
Title: Differential Antibody Recognition by Novel SARS-CoV-2 and SARS-CoV Spike Protein Receptor Binding Domains: Mechanistic Insights and Implications for the Design of Diagnostics and Therapeutics Document date: 2020_3_14
ID: c08ptb1o_2
Snippet: In this context, structural knowledge of the proteins of the virus can provide important information to develop strategies against the infection, ranging from diagnosis to therapy. In general, coronaviruses use this protein localized on the envelope to bind their cell receptors. After binding, a series of molecular events lead to the fusion of the viral membrane with that of the host cell, eventually leading to virus entry and invasion......
Document: In this context, structural knowledge of the proteins of the virus can provide important information to develop strategies against the infection, ranging from diagnosis to therapy. In general, coronaviruses use this protein localized on the envelope to bind their cell receptors. After binding, a series of molecular events lead to the fusion of the viral membrane with that of the host cell, eventually leading to virus entry and invasion.
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