Selected article for: "cross reaction and detection sensitivity"
Author: Minghua Jiang; Wenjie Fang; Amir Aratehfar; Xiaojing Li; Liyan ling; Hua Fang; Farnaz Farnaz Daneshnia; Jian Yu; Wanqing Liao; Hao Pei; Weihua Pan; Cornelia Lass-Florl
Title: Development and validation of a rapid single-step reverse transcriptase loop-mediated isothermal amplification (RT-LAMP) system potentially to be used for reliable and high-throughput screening of COVID-19
  • Document date: 2020_3_20
    • ID: eo2pcgix_1
    Snippet: Primers showing optimal in-silico features were subjected to analytical sensitivity and 25 specificity to assess the limit of detection (LOD) and cross-reaction with closely-and distantly-26 related viral species, and clinically prominent bacterial and fungal species. In order to evaluate the 27 clinical utility, our RT-LAMP was subjected to a large number of clinical samples, including 213 28 negative and 47 positive patients, relative to two co.....
    Document: Primers showing optimal in-silico features were subjected to analytical sensitivity and 25 specificity to assess the limit of detection (LOD) and cross-reaction with closely-and distantly-26 related viral species, and clinically prominent bacterial and fungal species. In order to evaluate the 27 clinical utility, our RT-LAMP was subjected to a large number of clinical samples, including 213 28 negative and 47 positive patients, relative to two commercial quantitative RT-PCR assays. 29

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