Author: Bo Diao; Kun Wen; Jian Chen; Yueping Liu; Zilin Yuan; Chao Han; Jiahui Chen; Yuxian Pan; Li Chen; Yunjie Dan; Jing Wang; Yongwen Chen; Guohong Deng; Hongwei Zhou; Yuzhang Wu
Title: Diagnosis of Acute Respiratory Syndrome Coronavirus 2 Infection by Detection of Nucleocapsid Protein Document date: 2020_3_10
ID: 5xxi33v3_27
Snippet: infections, but the use of novel coronavirus antigen for diagnosis has not been successfully developed. Now, the virus (SARS-CoV-2) nucleic acid RT-PCR test has become the standard method for diagnosis of SARS-CoV-2 infection due to its high detection rate [12] . However, nucleic acid test results are sometimes unstable and take too long, or can appear false negative and false positive. Moreover, IgM and IgG antibody detection method have been us.....
Document: infections, but the use of novel coronavirus antigen for diagnosis has not been successfully developed. Now, the virus (SARS-CoV-2) nucleic acid RT-PCR test has become the standard method for diagnosis of SARS-CoV-2 infection due to its high detection rate [12] . However, nucleic acid test results are sometimes unstable and take too long, or can appear false negative and false positive. Moreover, IgM and IgG antibody detection method have been used in diagnosing with a relative higher positive rate [13] . However, virus-specific antibody usually produced in 2-4 weeks after infection.
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