Selected article for: "modeled structure and solved structure"
Author: Ilda D’Annessa; Filippo Marchetti; Giorgio Colombo
Title: Differential Antibody Recognition by Novel SARS-CoV-2 and SARS-CoV Spike Protein Receptor Binding Domains: Mechanistic Insights and Implications for the Design of Diagnostics and Therapeutics
  • Document date: 2020_3_14
    • ID: c08ptb1o_18
    Snippet: In this complex scenario, our predictions can help disentangle some of the issues related to betacoronavirues infectivity and immunological response. Acknowledgement We acknowledge funding by Regione Lombardia, project READY (Regional Network for developing diagnostic methods in rapid response to emerging epidemics and bio-emergencies) Missing residues belonging to highly flexible loops not solved in the structure of the Spike protein were modele.....
    Document: In this complex scenario, our predictions can help disentangle some of the issues related to betacoronavirues infectivity and immunological response. Acknowledgement We acknowledge funding by Regione Lombardia, project READY (Regional Network for developing diagnostic methods in rapid response to emerging epidemics and bio-emergencies) Missing residues belonging to highly flexible loops not solved in the structure of the Spike protein were modeled by homology using the SwissModel web server (https://swissmodel.expasy.org/), that retrieved the structure of the SARS-CoV 5x58 as the best template.

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