Selected article for: "clinical outcome and ensemble gene noise"
Author: Tristan de Jong; Victor Guryev; Yury M. Moshkin
Title: Discovery of pharmaceutically-targetable pathways and prediction of survivorship for pneumonia and sepsis patients from the view point of ensemble gene noise
  • Document date: 2020_4_11
    • ID: f5w05rc2_35
    Snippet: In conclusion, here we showed a potential of ensemble gene noise in the biological interpretation of a disease, the identification of pharmaceutically targetable pathways, novel biomarkers, and the prediction of clinical outcome. Together, we believe that ensemble gene noise analysis could be broadly applied alongside with DGE to dissect molecular mechanisms of the pathology in two complementary dimensions: in Jacob-Monod dimension of specific ge.....
    Document: In conclusion, here we showed a potential of ensemble gene noise in the biological interpretation of a disease, the identification of pharmaceutically targetable pathways, novel biomarkers, and the prediction of clinical outcome. Together, we believe that ensemble gene noise analysis could be broadly applied alongside with DGE to dissect molecular mechanisms of the pathology in two complementary dimensions: in Jacob-Monod dimension of specific gene regulation and in a novel dimension of holistic gene circuit regulation.

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