Author: Ilda D’Annessa; Filippo Marchetti; Giorgio Colombo
Title: Differential Antibody Recognition by Novel SARS-CoV-2 and SARS-CoV Spike Protein Receptor Binding Domains: Mechanistic Insights and Implications for the Design of Diagnostics and Therapeutics Document date: 2020_3_14
ID: c08ptb1o_10
Snippet: The application of MLCE to the Receptor Binding Domain (RBD, aa 319-591) of the SARS-CoV-2 spike protein (pdb code 6vsb; doi: 10.2210/pdb6vsb/pdb) 15 and of the SARS-CoV spike protein (pdb code 5x58; doi: 10.2210/pdb5X58/pdb) ( Figure 1 ) shows that the two protein regions that contain potential interaction regions/Ab-binding epitopes share the same topological localization at the two opposite ends of the 3D structures ( Figure 1 ). However, this.....
Document: The application of MLCE to the Receptor Binding Domain (RBD, aa 319-591) of the SARS-CoV-2 spike protein (pdb code 6vsb; doi: 10.2210/pdb6vsb/pdb) 15 and of the SARS-CoV spike protein (pdb code 5x58; doi: 10.2210/pdb5X58/pdb) ( Figure 1 ) shows that the two protein regions that contain potential interaction regions/Ab-binding epitopes share the same topological localization at the two opposite ends of the 3D structures ( Figure 1 ). However, this trait appears to be the only common one. The linear sequences that correspond to the predicted interacting epitope regions are reported in Table 1 .
Search related documents:
Co phrase search for related documents- epitope region and interaction region: 1, 2, 3
- epitope region and protein region: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- epitope region and SARS CoV spike protein: 1, 2, 3, 4, 5, 6, 7, 8
- epitope region and SARS spike: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- epitope region and SARS spike protein: 1, 2, 3, 4, 5, 6, 7, 8
- epitope region and spike protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
- interaction region and pdb code: 1
- interaction region and protein region: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- interaction region and SARS CoV spike protein: 1, 2, 3, 4, 5, 6, 7, 8
- interaction region and SARS spike: 1, 2, 3, 4, 5, 6, 7
- interaction region and SARS spike protein: 1, 2, 3, 4, 5
- interaction region and spike protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
- linear sequence and protein region: 1, 2
- linear sequence and SARS CoV spike protein: 1
- linear sequence and SARS spike: 1, 2, 3, 4
- linear sequence and SARS spike protein: 1, 2
- linear sequence and spike protein: 1, 2, 3, 4, 5
- pdb code and SARS CoV spike protein: 1
- pdb code and SARS spike: 1, 2
Co phrase search for related documents, hyperlinks ordered by date