Author: Naser Al Awaji, Nisreen; Talal Ahmedah, Hanadi; Mohammed Alsaady, Isra; Ahmed Bawaked, Rowaedh; Alraey, Mohammed A.; Ayed Alasiri, Ahmed; Mofareh Alfaifi, Abdullah; Ali Alshehri, Hamdan; Alserihi, Raed; Yasin, Elrashed B.
Title: Validation and Performance Comparison of Two SARS-CoV-2 IgG/IgM Rapid Tests Cord-id: 1snzwl2r Document date: 2021_3_14
ID: 1snzwl2r
Snippet: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a disease called COVID-19. COVID-19 is primarily diagnosed using molecular techniques mainly real-time reverse transcriptase PCR. Reliable and accurate serologic assays for COVID-19, are an important tool for surveillance and epidemiologic studies. In this study, the IgG/IgM Rapid Test Cassette and the Prima COVID-19 IgG/IgM Rapid Test for the detection of SARS-CoV-2 antibodies in blood, serum and plasma samples collected from p
Document: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a disease called COVID-19. COVID-19 is primarily diagnosed using molecular techniques mainly real-time reverse transcriptase PCR. Reliable and accurate serologic assays for COVID-19, are an important tool for surveillance and epidemiologic studies. In this study, the IgG/IgM Rapid Test Cassette and the Prima COVID-19 IgG/IgM Rapid Test for the detection of SARS-CoV-2 antibodies in blood, serum and plasma samples collected from patients up to 48 days after symptom onset in Saudi Arabia were validated. Overall, both tests showed poor performance and cannot be utilised for COVID-19 diagnosis as a point of care test or to determine seroprevalence.
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