Selected article for: "JIP1 role and JNK interact"
Author: Alexa C. Robitaille; Elise Caron; Nicolas Zucchini; Espérance Mukawera; Damien Adam; Mélissa K. Mariani; Anaïs Gélinas; Audray Fortin; Emmanuelle Brochiero; Nathalie Grandvaux
Title: DUSP1 regulates apoptosis and cell migration, but not the JIP1-protected cytokine response, during Respiratory Syncytial Virus and Sendai Virus infection
  • Document date: 2017_7_13
    • ID: jzzhpw7h_12
    Snippet: Scaffolding proteins of the JIP family interact with distinct pools of JNK to specifically place them next to their upstream activators and downstream substrate mediating specific functional pathways 41,42 . Therefore, we aimed to investigate the role of JIP proteins in RSV-and SeVinduced JNK activation and regulation by DUSP1. The JIP family is composed of 4 members, JIP1-4, with distinct expression profiles. Here, we assessed the role of JIP1 a.....
    Document: Scaffolding proteins of the JIP family interact with distinct pools of JNK to specifically place them next to their upstream activators and downstream substrate mediating specific functional pathways 41,42 . Therefore, we aimed to investigate the role of JIP proteins in RSV-and SeVinduced JNK activation and regulation by DUSP1. The JIP family is composed of 4 members, JIP1-4, with distinct expression profiles. Here, we assessed the role of JIP1 and JIP3 in A549 cells based on previous reports indicative of their expression in lung cells [43] [44] [45] [46] . In contrary, JIP2 was shown to be restricted to human brain 47 and human JIP4 was found only in testis 48, 49 . First, we tested the interaction between JNK and JIP1 or JIP3 during SeV and RSV infection.

    Search related documents:
    Co phrase search for related documents
    • DUSP1 regulation and JIP family: 1
    • DUSP1 regulation and JIP protein: 1
    • DUSP1 regulation and rsv infection: 1, 2, 3, 4, 5, 6, 7
    • expression profile and functional pathway: 1, 2, 3
    • expression profile and human brain: 1, 2
    • expression profile and lung cell: 1, 2, 3, 4, 5, 6, 7
    • expression profile and lung cell expression: 1, 2
    • expression profile and rsv infection: 1, 2
    • functional pathway and lung cell: 1
    • functional pathway and rsv infection: 1
    • human brain and lung cell: 1, 2
    • human brain and lung cell expression: 1
    • JIP family and rsv infection: 1
    • JIP protein and rsv infection: 1
    • lung cell and previous report: 1, 2, 3
    • lung cell and rsv infection: 1, 2, 3, 4, 5, 6