Author: Saglio, Francesco; Hanley, Patrick J; Bollard, Catherine M
Title: THE TIME IS NOW: MOVING TOWARDS VIRUS-SPECIFIC T CELLS AFTER ALLOGENIC HEMATOPOIETIC STEM CELL TRANSPLANTATION AS THE STANDARD OF CARE Cord-id: 3rbjwjxu Document date: 2014_2_1
ID: 3rbjwjxu
Snippet: Adoptive immunotherapy—in particulary T cell therapy—has recently emerged as a useful strategy with the potential to overcome many of the limitations of antiviral drugs for the treatment of viral complications after hematopietic stem cell transplantation (HSCT). In this review we briefly summarize the current methods for virus- specific T cell isolation or selection and we report results from clinical trials employing these techniques, focusing specifically on the strategies aimed to broaden
Document: Adoptive immunotherapy—in particulary T cell therapy—has recently emerged as a useful strategy with the potential to overcome many of the limitations of antiviral drugs for the treatment of viral complications after hematopietic stem cell transplantation (HSCT). In this review we briefly summarize the current methods for virus- specific T cell isolation or selection and we report results from clinical trials employing these techniques, focusing specifically on the strategies aimed to broaden the application of this technology.
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