Author: Haixia Su; Sheng Yao; Wenfeng Zhao; Minjun Li; Jia Liu; Weijuan Shang; Hang Xie; Changqiang Ke; Meina Gao; Kunqian Yu; Hong Liu; Jingshan Shen; Wei Tang; Leike Zhang; Jianping Zuo; Hualiang Jiang; Fang Bai; Yan Wu; Yang Ye; Yechun Xu
Title: Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro Document date: 2020_4_14
ID: ixun0c8g_41
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.13.038687 doi: bioRxiv preprint combined by peaks on UV (280 and 320 nm) and ELSD detectors. Totally 14 fractions were obtained with a recovery rate of 92% for the assay of SARS-CoV-2-3CLpro inhibition. For ligand binding screening and dissociation constant (Kd) determination, the magnitude size was set to 128 K and 1000 single scans were.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.13.038687 doi: bioRxiv preprint combined by peaks on UV (280 and 320 nm) and ELSD detectors. Totally 14 fractions were obtained with a recovery rate of 92% for the assay of SARS-CoV-2-3CLpro inhibition. For ligand binding screening and dissociation constant (Kd) determination, the magnitude size was set to 128 K and 1000 single scans were added. author/funder. All rights reserved. No reuse allowed without permission.
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