Author: Quaglino, P.; Fava, P.; Brizio, M.; Marra, E.; Rubatto, M.; Agostini, A.; Tonella, L.; Ribero, S.; Fierro, M. T.
Title: Metastatic melanoma treatment with checkpoint inhibitors in the COVIDâ€19 era: experience from an Italian Skin Cancer Unit Cord-id: 2gjb0usv Document date: 2020_6_4
ID: 2gjb0usv
Snippet: Melanoma epidemiology has shown a constant increase in the last few decades even if mortality is low and only a small percentage of patients develop metastatic disease. For these patients, immunotherapy with checkpoint inhibitors (ICI) significantly improves disease outcome with a median survival more than 2 years. The same drugs are used as adjuvant treatment in disease-free patients. Coronavirus Disease-19 (COVID-19) is now a pandemic disease with lung manifestations, which can bring severe ac
Document: Melanoma epidemiology has shown a constant increase in the last few decades even if mortality is low and only a small percentage of patients develop metastatic disease. For these patients, immunotherapy with checkpoint inhibitors (ICI) significantly improves disease outcome with a median survival more than 2 years. The same drugs are used as adjuvant treatment in disease-free patients. Coronavirus Disease-19 (COVID-19) is now a pandemic disease with lung manifestations, which can bring severe acute respiratory distress. The most important risk factors related to a higher death risk for COVID-19 pneumonia are elderly age and comorbidities (hypertension, diabetes, previous cancer).
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