Selected article for: "application wide range and wide range"

Author: Zheng, Mingyue; Liu, Xian; Xu, Yuan; Li, Honglin; Luo, Cheng; Jiang, Hualiang
Title: Computational methods for drug design and discovery: focus on China
  • Cord-id: 11halnby
  • Document date: 2013_9_11
  • ID: 11halnby
    Snippet: In the past decades, China's computational drug design and discovery research has experienced fast development through various novel methodologies. Application of these methods spans a wide range, from drug target identification to hit discovery and lead optimization. In this review, we firstly provide an overview of China's status in this field and briefly analyze the possible reasons for this rapid advancement. The methodology development is then outlined. For each selected method, a short bac
    Document: In the past decades, China's computational drug design and discovery research has experienced fast development through various novel methodologies. Application of these methods spans a wide range, from drug target identification to hit discovery and lead optimization. In this review, we firstly provide an overview of China's status in this field and briefly analyze the possible reasons for this rapid advancement. The methodology development is then outlined. For each selected method, a short background precedes an assessment of the method with respect to the needs of drug discovery, and, in particular, work from China is highlighted. Furthermore, several successful applications of these methods are illustrated. Finally, we conclude with a discussion of current major challenges and future directions of the field.

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