Clinical characteristics of the recovered COVID-19 patients with re-detectable positive RNA test

Jianghong An; Xuejiao Liao; Tongyang Xiao; Shen Qian; Jing Yuan; Haocheng Ye; Furong Qi; Chengguang Shen; Yang Liu; Lifei Wang; Xiaoya Cheng; Na Li; Qingxian Cai; Fang Wang; Jun Chen; Yingxia Liu; Yunfang Wang; Feng Zhang; Yang Fu; Xiaohua Tan; Lei Liu; Zheng Zhang

It revealed that the vast majority of RP patients (97.4%, n = 37) were younger than 60 years of age. Among them, patients younger than 14 years old were more common compared with those between the ages of 14 and 60 years (35.0% vs 16.0%, p < 0.01) ( Table 1 ). In addition, it is found that 36.7% (11/38) of RP patients are characterized by mild symptoms. The percentage was significantly higher than what was seen among NRP patients (12.7%, 19/204, p < 0.01, Supplemental Table 1 ). There was no significant difference in the gender distribution. Notably, there were less mild RP patients having fever in their initial symptoms as compared to mild NRP patients (p < 0.01). Also, 45.5% of mild RP patients displayed only upper respiratory symptoms at the first admission, while mild NRP patients usually had lower respiratory symptoms at the first admission (Table 1 ). There is no difference of the extent of lesions in the first chest CT imaging between RP and NRP patients with moderate stages. However, the incidence of RP (85.2%) was found to be particularly closely related to the sustained remission of chest CT imaging as compared to NRP patients, of which 36.2% displayed transient progression during their first hospitalization period (Table 1 and Figure 1 ). There was no significant difference in the usage of steroid and antiviral therapy between RP and NRP patients during their first hospitalization period. In addition, RP patients did not show a higher incidence of a history of traveling and living in Hubei province as compared to NRP patients. All rights reserved. No reuse allowed without permission. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.