Author: Matteo De Chiara; Benjamin Barré; Karl Persson; Amadi Onyetuga Chioma; Agurtzane Irizar; Joseph Schacherer; Jonas Warringer; Gianni Liti
Title: Domestication reprogrammed the budding yeast life cycle Document date: 2020_2_9
ID: hwvr0v8c_23
Snippet: . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.08.939314 doi: bioRxiv preprint Because sporulation effects of rare or clade specific variants evade GWAS detection 47 , we instead traced their effects by pinpointing likely loss-of-function variants in known sporulation and meiosis genes (n=251; Suppleme.....
Document: . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.08.939314 doi: bioRxiv preprint Because sporulation effects of rare or clade specific variants evade GWAS detection 47 , we instead traced their effects by pinpointing likely loss-of-function variants in known sporulation and meiosis genes (n=251; Supplementary table S3) and through known sporulation QTNs 46, 48, 49 . Meiotic genes often carried loss-of-function variants in domesticated lineages, but rarely in wild yeasts (Fig. 3e)
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