Author: Sánchez, Carlos M.; Jiménez, Gustavo; Laviada, MarÃa D.; Correa, Isabel; Suñé, Carlos; Bullido, MarÃa J.; Gebauer, Fátima; Smerdou, Cristian; Callebaut, Paul; Escribano, JoséM.; Enjuanes, Luis
Title: Antigenic homology among coronaviruses related to transmissible gastroenteritis virus Cord-id: 2jma4aqu Document date: 1990_2_28
ID: 2jma4aqu
Snippet: Abstract The antigenic homology of 26 coronavirus isolates, of which 22 were antigenically related to transmissible gastroenteritis virus (TGEV), was determined with 42 monoclonal antibodies. Type, group, and interspecies specific epitopes were defined. Two group specific MAbs distinguished the enteric TGEV isolates from the respiratory variants. An antigenic subsite involved in neutralization was conserved in porcine, feline, and canine coronavirus. The classification of the human coronavirus 2
Document: Abstract The antigenic homology of 26 coronavirus isolates, of which 22 were antigenically related to transmissible gastroenteritis virus (TGEV), was determined with 42 monoclonal antibodies. Type, group, and interspecies specific epitopes were defined. Two group specific MAbs distinguished the enteric TGEV isolates from the respiratory variants. An antigenic subsite involved in neutralization was conserved in porcine, feline, and canine coronavirus. The classification of the human coronavirus 229E in a taxonomic cluster distinct from TGEV group is suggested.
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