Early Prediction of Disease Progression in 2019 Novel Coronavirus Pneumonia Patients Outside Wuhan with CT and Clinical Characteristics

Zhichao Feng; Qizhi Yu; Shanhu Yao; Lei Luo; Junhong Duan; Zhimin Yan; Min Yang; Hongpei Tan; Mengtian Ma; Ting Li; Dali Yi; Ze Mi; Huafei Zhao; Yi Jiang; Zhenhu He; Huiling Li; Wei Nie; Yin Liu; Jing Zhao; Muqing Luo; Xuanhui Liu; Pengfei Rong; Wei Wang

Demographic, epidemiological, and laboratory data were obtained with data collection forms from electronic medical records. According to the source of infection, patients were divided into imported group (patients who had recently been to Wuhan) and nonimported group (patients who contacted with people from Wuhan or local infected patients). The clinical classification of NCP are as follows: (1) moderate type, patients with fever, respiratory tract symptoms, and radiological evidence of confirmed pneumonia. (2) severe type, patients with one of the following: a) respiratory distress (respiratory rate ≥ 30 beats/min); b) hypoxia (oxygen saturation ≤ 93% in the resting state); c) hypoxemia (arterial blood oxygen partial pressure/oxygen concentration ≤ 300mmHg). (3) critical type, patients with one of the following: a) respiratory failure requiring mechanical ventilation; b) shock; c) intensive care unit (ICU) admission is required for combined other organs failure. In this study, severe NCP broadly included severe and critical types as above defined. The endpoint of this study was the development of severe NCP, and patients who discharged or did not developed severe NCP at enrollment were censored.