Author: Laura Riva; Shuofeng Yuan; Xin Yin; Laura Martin-Sancho; Naoko Matsunaga; Sebastian Burgstaller-Muehlbacher; Lars Pache; Paul P. De Jesus; Mitchell V. Hull; Max Chang; Jasper Fuk-Woo Chan; Jianli Cao; Vincent Kwok-Man Poon; Kristina Herbert; Tu-Trinh Nguyen; Yuan Pu; Courtney Nguyen; Andrey Rubanov; Luis Martinez-Sobrido; Wen-Chun Liu; Lisa Miorin; Kris M. White; Jeffrey R. Johnson; Christopher Benner; Ren Sun; Peter G. Schultz; Andrew Su; Adolfo Garcia-Sastre; Arnab K. Chatterjee; Kwok-Yung Yuen; Sumit K. Chanda
Title: A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals Document date: 2020_4_17
ID: 1fgnfh62_51
Snippet: These selected compounds were tested in an orthogonal assay that directly measures viral replication, in contrast to the indirect measurement of replication assessed by CPE. Here, we took advantage of a high-throughput immunofluorescence assay that monitors infection levels as reflected by SARS-CoV-2 N protein expression at a single cell resolution. Importantly, this validation step enables the separation of author/funder. All rights reserved. No.....
Document: These selected compounds were tested in an orthogonal assay that directly measures viral replication, in contrast to the indirect measurement of replication assessed by CPE. Here, we took advantage of a high-throughput immunofluorescence assay that monitors infection levels as reflected by SARS-CoV-2 N protein expression at a single cell resolution. Importantly, this validation step enables the separation of author/funder. All rights reserved. No reuse allowed without permission.
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