Selected article for: "cell cell and control virus"
Author: Arunachalam Ramaiah; Deisy Contreras; Vineela Gangalapudi; Masumi Sameer Padhye; Jie Tang; Vaithilingaraja Arumugaswami
Title: Dysregulation of Long Non-coding RNA (lncRNA) Genes and Predicted lncRNA-Protein Interactions during Zika Virus Infection
  • Document date: 2016_7_1
    • ID: 2cerplno_34
    Snippet: NEAT1 is present in the nuclear paraspeckle structures [35, 36] . Both of these lncRNAs have been shown to be upregulated in cancer cells and to be involved in cell proliferation [31, 33, [37] [38] [39] [40] . Depletion of these lncRNAs can cause loss of cell proliferation and cell cycle arrest. ZIKV has been shown to cause cell cycle inhibition and neuronal cell death [41] . These observations allow us to formulate a hypothesis that ZIKV may reg.....
    Document: NEAT1 is present in the nuclear paraspeckle structures [35, 36] . Both of these lncRNAs have been shown to be upregulated in cancer cells and to be involved in cell proliferation [31, 33, [37] [38] [39] [40] . Depletion of these lncRNAs can cause loss of cell proliferation and cell cycle arrest. ZIKV has been shown to cause cell cycle inhibition and neuronal cell death [41] . These observations allow us to formulate a hypothesis that ZIKV may regulate MALAT1 and NEAT1 for cell cycle control towards completing virus replication. This investigation was carried out in a ZIKV proteins and other biomolecules [42, 43] . The RNA-protein interactions, which are known to facilitate post-transcriptional regulatory networks, are beginning to be understood [27] [28] [29] .

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