Author: Lennon, Niall J; Bhattacharyya, Roby P; Mina, Michael J; Rehm, Heidi L; Hung, Deborah T; Smole, Sandra; Woolley, Ann; Lander, Eric S; Gabriel, Stacey B
Title: Cross-sectional assessment of SARS-CoV-2 viral load by symptom status in Massachusetts congregate living facilities Cord-id: 303x0fhz Document date: 2021_7_13
ID: 303x0fhz
Snippet: Transmission of COVID-19 from people without symptoms confounds societal mitigation strategies. From April to June 2020, we tested nasopharyngeal swabs by RT-qPCR from 15,514 staff and 16,966 residents of nursing homes and assisted living facilities in Massachusetts. Cycle threshold (Ct) distributions were very similar between populations with (N = 739) and without (N = 2179) symptoms at the time of sampling (mean Ct 25.7 versus 26.4, ranges 12-38). However, as local cases waned, those without s
Document: Transmission of COVID-19 from people without symptoms confounds societal mitigation strategies. From April to June 2020, we tested nasopharyngeal swabs by RT-qPCR from 15,514 staff and 16,966 residents of nursing homes and assisted living facilities in Massachusetts. Cycle threshold (Ct) distributions were very similar between populations with (N = 739) and without (N = 2179) symptoms at the time of sampling (mean Ct 25.7 versus 26.4, ranges 12-38). However, as local cases waned, those without symptoms shifted towards higher Ct. With such similar viral load distributions, existing testing modalities should perform comparably regardless of symptoms, contingent upon time since infection.
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