Author: Maoz-Segal, Ramit; Andrade, Paulo
Title: Molecular Mimicry and Autoimmunity Cord-id: 39jux8wj Document date: 2015_2_6
ID: 39jux8wj
Snippet: The term Molecular mimicry describes the sequence similarity between foreign (microorganism's peptides) and self peptides (the host's antigen). This phenomenon has been recently discovered as a one of the major mechanism in which there is a break-down of self-tolerance of the immune system following autoimmunity. After a short preface, the chapter contains examples of common infectious agents and their role in autoimmune diseases. Later on, it describes the autoimmune diseases in which there was
Document: The term Molecular mimicry describes the sequence similarity between foreign (microorganism's peptides) and self peptides (the host's antigen). This phenomenon has been recently discovered as a one of the major mechanism in which there is a break-down of self-tolerance of the immune system following autoimmunity. After a short preface, the chapter contains examples of common infectious agents and their role in autoimmune diseases. Later on, it describes the autoimmune diseases in which there was found a relation to infectious agents via molecular mimicry mechanism. The data is summarized in two tables.
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