Author: Awad, Samir Mohamed; Ali, Shima Mahmoud; Mansour, Yara Essam; Fatahala, Samar Said
Title: Synthesis and Evaluation of Some Uracil Nucleosides as Promising Anti-Herpes Simplex Virus 1 Agents Cord-id: 2rupdwhz Document date: 2021_5_18
ID: 2rupdwhz
Snippet: Since herpes simplex virus type 1 (HSV-1) infection is so widespread, several antiviral drugs have been developed to treat it, among which are uracil nucleosides. However, there are major problems with the current medications such as severe side-effects and drug resistance. Here we present some newly synthesized cyclic and acyclic uracil nucleosides that showed very promising activity against HSV-1 compared to acyclovir.
Document: Since herpes simplex virus type 1 (HSV-1) infection is so widespread, several antiviral drugs have been developed to treat it, among which are uracil nucleosides. However, there are major problems with the current medications such as severe side-effects and drug resistance. Here we present some newly synthesized cyclic and acyclic uracil nucleosides that showed very promising activity against HSV-1 compared to acyclovir.
Search related documents:
Co phrase search for related documents- action mode and low toxicity: 1, 2, 3, 4
- action mode investigation and low activity: 1
Co phrase search for related documents, hyperlinks ordered by date