Author: Riccardo Delli ponti; Alexandros Armaos; Stefanie Marti; Gian Gaetano Tartaglia
Title: A method for RNA structure prediction shows evidence for structure in lncRNAs Document date: 2018_4_16
ID: jb447ndz_15
Snippet: We developed the CROSSalign method based on the combination of the CROSS algorithm to predict the RNA secondary structure at single-nucleotide resolution [10] and the Dynamic Time Warping (DTW) algorithm to align profiles of different lengths [11] . DTW has been previously applied in different fields, especially pattern recognition and data mining [34, 35] , but has never been used to investigate structural alignments of RNA molecules. Since CROS.....
Document: We developed the CROSSalign method based on the combination of the CROSS algorithm to predict the RNA secondary structure at single-nucleotide resolution [10] and the Dynamic Time Warping (DTW) algorithm to align profiles of different lengths [11] . DTW has been previously applied in different fields, especially pattern recognition and data mining [34, 35] , but has never been used to investigate structural alignments of RNA molecules. Since CROSS has no sequence length restrictions and shows strong performances on both coding and non-coding RNAs [10] the combination with DTW allows very accurate comparisons of structural profiles.
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