Author: Riccardo Delli ponti; Alexandros Armaos; Stefanie Marti; Gian Gaetano Tartaglia
Title: A method for RNA structure prediction shows evidence for structure in lncRNAs Document date: 2018_4_16
ID: jb447ndz_17
Snippet: We applied CROSSalign to investigate the structural conservation of lncRNAs in different species and the complete genomes of ssRNA viruses. We found that the algorithm is able to find structural homologues between thousands of matches and correctly identifies the regions of similarity between profiles of different lengths. The results of our analysis reveal a structural conservation between known lncRNA domains including XIST RepA (best hit out o.....
Document: We applied CROSSalign to investigate the structural conservation of lncRNAs in different species and the complete genomes of ssRNA viruses. We found that the algorithm is able to find structural homologues between thousands of matches and correctly identifies the regions of similarity between profiles of different lengths. The results of our analysis reveal a structural conservation between known lncRNA domains including XIST RepA (best hit out of 8176 cases; 95% overlap with the query region) and HOTAIR D2 (best hit out of 8176 cases; 78% overlap with the
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