Author: Shuya Lu; Qi Zhou; Liping Huang; Qianling Shi; Siya Zhao; Zijun Wang; Weiguo Li; Yuyi Tang; Yanfang Ma; Xufei Luo; Toshio Fukuoka; Hyeong Sik Ahn; Myeong Soo Lee; Zhengxiu Luo; Enmei Liu; Yaolong Chen; Chenyan Zhou; Donghong Peng
Title: Effectiveness and Safety of Glucocorticoids to Treat COVID-19: A Rapid Review and Meta-Analysis Document date: 2020_4_22
ID: 935r7w01_26
Snippet: Two researchers (Zhou Q and Shi Q) assessed the quality of evidence independently using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) tool (19) (20) . We produced a "Summary of Findings" table using the GRADEpro software. The quality of evidence can be downgraded based on five factors (study limitations, consistency of effect, imprecision, indirectness and publication bias) and upgraded based on three factors (larg.....
Document: Two researchers (Zhou Q and Shi Q) assessed the quality of evidence independently using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) tool (19) (20) . We produced a "Summary of Findings" table using the GRADEpro software. The quality of evidence can be downgraded based on five factors (study limitations, consistency of effect, imprecision, indirectness and publication bias) and upgraded based on three factors (large magnitude of effect, dose-response relation and plausible confounders or biases) (21) (22) (23) (24) (25) (26) . The quality of evidence of each outcome is then classified as "high", "moderate", "low" or "very low".
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