Author: Lee, Nelson; Chan, Martin C. W.; Lui, Grace C. Y.; Li, Ran; Wong, Rity Y. K.; Yung, Irene M. H.; Cheung, Catherine S. K.; Chan, Eugenia C. Y.; Hui, David S. C.; Chan, Paul K. S.
Title: High Viral Load and Respiratory Failure in Adults Hospitalized for Respiratory Syncytial Virus Infections Cord-id: 1mrds1m6 Document date: 2015_10_15
ID: 1mrds1m6
Snippet: A prospective study among adults hospitalized for polymerase chain reaction–confirmed respiratory syncytial virus infections (n = 123) showed frequent occurrence of lower respiratory-tract complications causing respiratory insufficiency (52.8%), requirement for assisted ventilation (16.3%), and intensive care unit admission/death (12.2%). High viral RNA concentration was detected at time of hospitalization, including in patients who presented later than 2 days of illness (day 1–2, 7.29 ± 1.
Document: A prospective study among adults hospitalized for polymerase chain reaction–confirmed respiratory syncytial virus infections (n = 123) showed frequent occurrence of lower respiratory-tract complications causing respiratory insufficiency (52.8%), requirement for assisted ventilation (16.3%), and intensive care unit admission/death (12.2%). High viral RNA concentration was detected at time of hospitalization, including in patients who presented later than 2 days of illness (day 1–2, 7.29 ± 1.47; day 3–4, 7.28 ± 1.41; day 5–8, 6.66 ± 1.87 log(10) copies/mL). RNA concentration was independently associated with risk of complications and respiratory insufficiency (adjusted odds ratio 1.40 per log(10) copies/mL increase, 95% confidence interval, 1.03–1.90; P = .034). Our data indicate the need and provide a basis for clinical research on antiviral therapy in this population.
Search related documents:
Co phrase search for related documents- acute coronary syndrome and logistic regression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- acute coronary syndrome and logistic regression model: 1, 2
- acute exacerbation and admission time: 1, 2, 3
- acute exacerbation and logistic regression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- acute exacerbation and logistic regression model: 1, 2
- acute exacerbation and low detection: 1
- acute exacerbation and low respiratory: 1
- acute respiratory infection and adequate sample: 1, 2
- acute respiratory infection and adjusted odd ratio: 1
- acute respiratory infection and admission time: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute respiratory infection and logistic regression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute respiratory infection and logistic regression model: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute respiratory infection and low detection: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- acute respiratory infection and low detection limit: 1
- acute respiratory infection and low respiratory: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute respiratory infection symptom and admission time: 1
- acute respiratory infection symptom and logistic regression: 1
- adequate sample and logistic regression: 1, 2, 3
- adjusted odd ratio and logistic regression model: 1, 2
Co phrase search for related documents, hyperlinks ordered by date