Author: Riccardo Delli ponti; Alexandros Armaos; Stefanie Marti; Gian Gaetano Tartaglia
Title: A method for RNA structure prediction shows evidence for structure in lncRNAs Document date: 2018_4_16
ID: jb447ndz_4
Snippet: To test the performances and functionality of CROSS combined with DTW ( Supplementary Figures 1 and 2) , we selected a dataset of 22 structures for which crystallographic (exact base pairing between nucleotides) and Selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE; chemical probing of flexible regions used to assess whether a nucleotide is in double-or single-stranded state) data are available [12] . Using DTW, we calculated th.....
Document: To test the performances and functionality of CROSS combined with DTW ( Supplementary Figures 1 and 2) , we selected a dataset of 22 structures for which crystallographic (exact base pairing between nucleotides) and Selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE; chemical probing of flexible regions used to assess whether a nucleotide is in double-or single-stranded state) data are available [12] . Using DTW, we calculated the structural distances between all possible pairs in the dataset considering crystallographic (dots and parentheses were transformed into binary code) data as well as 1) SHAPE profiles ( [20] .
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