Selected article for: "elispot assay and IFN Î elispot assay"
Author: Su, Zhiying; Hu, Wenjia; Liu, Qianyun; Zhang, Yongxi; Chen, Tielong; Zhou, Yingying; Zhang, Zhen; Chen, Yu; Yang, Rongrong; Xiong, Yong; Wang, Xinghuan
Title: Clinical and immunological characteristics in COVID-19 convalescent patients
  • Cord-id: 6xrezb67
  • Document date: 2021_10_9
    • ID: 6xrezb67
    Snippet: The humoral and cellular immunity of convalescent COVID-19 patients is involved in pathogenesis and vaccine immunity. In this study, through CoV-psV neutralization assay and IFN-γ ELISpot testing in 30 cases of COVID-19 patients after 9 months post-SARS-CoV-2 infection, it found that the ratio of memory/naive CD4(+) T lymphocytes cells and levels of anti-SARS-CoV-2-IgM and RBD-IgM were slightly but significantly higher in COVID-19 severe convalescent patients than that in non-severe patients. T
    Document: The humoral and cellular immunity of convalescent COVID-19 patients is involved in pathogenesis and vaccine immunity. In this study, through CoV-psV neutralization assay and IFN-γ ELISpot testing in 30 cases of COVID-19 patients after 9 months post-SARS-CoV-2 infection, it found that the ratio of memory/naive CD4(+) T lymphocytes cells and levels of anti-SARS-CoV-2-IgM and RBD-IgM were slightly but significantly higher in COVID-19 severe convalescent patients than that in non-severe patients. The specific cellular and humoral immunity against SARS-CoV-2 were detectable, regardless of the severity of the disease in the acute phase. This information may help understanding the immune status after SARS-CoV-2 infection.

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