Author: Brierley, Ian; Dos Ramos, Francisco J.
Title: Programmed ribosomal frameshifting in HIV-1 and the SARS–CoV Cord-id: 2wuc5yiu Document date: 2005_11_28
ID: 2wuc5yiu
Snippet: Ribosomal frameshifting is a mechanism of gene expression used by several RNA viruses to express replicase enzymes. This article focuses on frameshifting in two human pathogens, the retrovirus human immunodeficiency virus type 1 (HIV-1) and the coronavirus responsible for severe acute respiratory syndrome (SARS). The nature of the frameshift signals of HIV-1 and the SARS–CoV will be described and the impact of this knowledge on models of frameshifting will be considered. The role of frameshift
Document: Ribosomal frameshifting is a mechanism of gene expression used by several RNA viruses to express replicase enzymes. This article focuses on frameshifting in two human pathogens, the retrovirus human immunodeficiency virus type 1 (HIV-1) and the coronavirus responsible for severe acute respiratory syndrome (SARS). The nature of the frameshift signals of HIV-1 and the SARS–CoV will be described and the impact of this knowledge on models of frameshifting will be considered. The role of frameshifting in the replication cycle of the two pathogens and potential antiviral therapies targeting frameshifting will also be discussed.
Search related documents:
Co phrase search for related documents- acute respiratory syndrome and adjacent residue: 1
Co phrase search for related documents, hyperlinks ordered by date