Selected article for: "CoV infection and immune mediate"
Author: Yin, Yun; Rohli, Kristen; Shen, Pengyue; Lu, Haonan; Liu, Yuenan; Dou, Qingyu; Zhang, Lin; Kong, Xiangyi; Yang, Shujuan; Jia, Peng
Title: The epidemiology, pathophysiological mechanisms, and management toward COVID-19 patients with Type 2 diabetes: a systematic review
  • Cord-id: 1h8udhzk
  • Document date: 2021_9_6
    • ID: 1h8udhzk
    Snippet: This review comprehensively summarizes epidemiologic evidence of COVID-19 in patients with Type 2 diabetes, explores pathophysiological mechanisms, and integrates recommendations and guidelines for patient management. We found that diabetes was a risk factor for diagnosed infection and poor prognosis of COVID-19. Patients with diabetes may be more susceptible to adverse outcomes associated with SARS-CoV-2 infection due to impaired immune function and possible upregulation of enzymes that mediate
    Document: This review comprehensively summarizes epidemiologic evidence of COVID-19 in patients with Type 2 diabetes, explores pathophysiological mechanisms, and integrates recommendations and guidelines for patient management. We found that diabetes was a risk factor for diagnosed infection and poor prognosis of COVID-19. Patients with diabetes may be more susceptible to adverse outcomes associated with SARS-CoV-2 infection due to impaired immune function and possible upregulation of enzymes that mediate viral invasion. The chronic inflammation caused by diabetes, coupled with the acute inflammatory reaction caused by SARS-CoV-2, results in a propensity for inflammatory storm. Patients with diabetes should be aware of their increased risk for COVID-19.

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