Selected article for: "host human and intermediate host"
Author: Yu Lei; yunping lan; jianli lu; xiaobo huang; bamu silang; fan zeng
Title: Clinical features of imported cases of coronavirus disease 2019 in Tibetan patients in the Plateau area
  • Document date: 2020_3_13
    • ID: 289fu2yb_21
    Snippet: Lymphocytopenia was common, especially in those with clinical symptoms, which is consistent with the data reported recently. Nearly half of patients showed increased levels of LDH, while one-third of patients suffered liver injury and decreased levels of prealbumin. However, these changes were mild. Angiotensin converting enzyme 2 (ACE2) may act as a potential intermediate host receptor which transmitting SARS-CoV-2 to human. ACE2 is expressed in.....
    Document: Lymphocytopenia was common, especially in those with clinical symptoms, which is consistent with the data reported recently. Nearly half of patients showed increased levels of LDH, while one-third of patients suffered liver injury and decreased levels of prealbumin. However, these changes were mild. Angiotensin converting enzyme 2 (ACE2) may act as a potential intermediate host receptor which transmitting SARS-CoV-2 to human. ACE2 is expressed in liver tissue and an overactive inflammatory response in patients with SARS-CoV-2 infection may cause increased ACE2 expression, and thus result in the observed liver tissue injury 5, 6 . Therefore, in addition to the obvious target organ of the lungs, the liver is another important organ that is vulnerable following infection with SARS-CoV-2.

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