Author: Medaglia, Alice Annalisa; Siracusa, Lucia; Gioè, Claudia; Giordano, Salvatore; Cascio, Antonio; Colomba, Claudia
Title: Kawasaki disease recurrence in the COVID-19 era: a systematic review of the literature Cord-id: 3g7kmk0j Document date: 2021_4_19
ID: 3g7kmk0j
Snippet: Kawasaki disease (KD) is a vasculitis of unknown origin of small and medium caliber blood vessels, especially involving coronary arteries and is the leading cause of acquired heart disease in childhood in developed countries. Although rarely, it can recur: most recurrences occur within 2 years of the initial episode. No data are available on incidence of recurrent KD in Europe and multiple recurrences are rarely seen. We reviewed the medical literature on Kawasaki disease recurrence and reported
Document: Kawasaki disease (KD) is a vasculitis of unknown origin of small and medium caliber blood vessels, especially involving coronary arteries and is the leading cause of acquired heart disease in childhood in developed countries. Although rarely, it can recur: most recurrences occur within 2 years of the initial episode. No data are available on incidence of recurrent KD in Europe and multiple recurrences are rarely seen. We reviewed the medical literature on Kawasaki disease recurrence and reported a new case of Kawasaki disease recurrence in a child with SARS-CoV-2 infection. We believe that in our case SARS Cov2 acted as a trigger capable to determine, in a genetically susceptible individual, a second recurrence of the disease. In the Covid-19 era we affirm the importance for Kawasaki disease to be tested for SARS Cov2 infection. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13052-021-01041-4.
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