Author: Ting Ding; Jinjin Zhang; Tian Wang; Pengfei Cui; Zhe Chen; Jingjing Jiang; Su Zhou; Jun Dai; Bo Wang; Suzhen Yuan; Wenqing Ma; Lingwei Ma; Yueguang Rong; Jiang Chang; Xiaoping Miao; Xiangyi Ma; Shixuan Wang
Title: A Multi-hospital Study in Wuhan, China:Protective Effects of Non-menopause and Female Hormones on SARS-CoV-2 infection Document date: 2020_3_30
ID: lplodn60_7
Snippet: In our attempt to address this question, we enrolled COVID-19 patients at Tongji Hospital and Mobile Cabin Hospital. As described below, we found that there are the sex differences in the severity and outcomes of this disease. Also, we showed there is a good correlation between menstruation status/hormone levels and the severity or outcomes of COVID-19. Finally, by examining the association between cytokines related to immunity and inflammation a.....
Document: In our attempt to address this question, we enrolled COVID-19 patients at Tongji Hospital and Mobile Cabin Hospital. As described below, we found that there are the sex differences in the severity and outcomes of this disease. Also, we showed there is a good correlation between menstruation status/hormone levels and the severity or outcomes of COVID-19. Finally, by examining the association between cytokines related to immunity and inflammation and disease severity, clinical outcomes or E2, we learned that E2 is inversely correlated with the levels of these cytokines. Our results demonstrate that the better clinical outcomes of female COVID-19 patients are well correlated with menstruation status and female hormone levels. were inquired by telephone follow-up with menstrual status and gynecologic history, 435 patients were finally included. The correlation between menstruation status and disease severity or outcomes were analyzed. We also tested serum cytokines related to All rights reserved. No reuse allowed without permission. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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