Author: Lakdawala, Seema S.; Menachery, Vineet
Title: Catch me if you can: Superspreading of SARS-CoV-2 Cord-id: 7momt81r Document date: 2021_5_11
ID: 7momt81r
Snippet: While significant insights have been gained around pathogenesis and progression of COVID-19, superspreading of coronaviruses remains a mystery. Cluster transmission of SARS-CoV-2 has been documented in many contact tracing studies, where the majority of new SARS-CoV-2 infections are linked to a relatively small portion of infected individuals. Interestingly, the genetic sequence of the virus, severity of disease, and underlying host parameters like age, sex, and health conditions are not correla
Document: While significant insights have been gained around pathogenesis and progression of COVID-19, superspreading of coronaviruses remains a mystery. Cluster transmission of SARS-CoV-2 has been documented in many contact tracing studies, where the majority of new SARS-CoV-2 infections are linked to a relatively small portion of infected individuals. Interestingly, the genetic sequence of the virus, severity of disease, and underlying host parameters like age, sex, and health conditions are not correlated with superspreading events. In this commentary, we will discuss what is known and unknown about coronavirus superspreader transmission and explore whether characteristics of the virion, the donor, or the environment contribute to this phenomenon.
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