Author: Zhang, Lin; Mai, Wuqian; Jiang, Wenyang; Geng, Qing
Title: Case Report: Pathologic Complete Response to Pembrolizumab in Combination With Neoadjuvant Chemotherapy in a Patient With Stage IIB Squamous Lung Cancer Cord-id: 2k19t65c Document date: 2020_11_27
ID: 2k19t65c
Snippet: The emergence of PD-1 antibodies has radically changed the therapeutic profiles of lung cancer, which has the highest incidence and mortality rate among all cancers worldwide. Pembrolizumab, an anti-PD-1 antibody, has been proven to have strong anti-tumor activity in a variety of clinical studies. Here, we described a patient with stage IIB squamous lung cancer who has benefited from a preoperative pembrolizumab plus chemotherapy regimen. The addition of pembrolizumab to neoadjuvant chemotherapy
Document: The emergence of PD-1 antibodies has radically changed the therapeutic profiles of lung cancer, which has the highest incidence and mortality rate among all cancers worldwide. Pembrolizumab, an anti-PD-1 antibody, has been proven to have strong anti-tumor activity in a variety of clinical studies. Here, we described a patient with stage IIB squamous lung cancer who has benefited from a preoperative pembrolizumab plus chemotherapy regimen. The addition of pembrolizumab to neoadjuvant chemotherapy before surgery led to a pathologic complete response and the avoidance of left pneumonectomy. This case highlights the effect of neoadjuvant pembrolizumab plus chemotherapy on non-small cell lung cancer patients and has provided a promising choice in future clinical practice.
Search related documents:
Co phrase search for related documents- abdominal ultrasonography and lymph node: 1, 2, 3, 4, 5, 6, 7, 8
- low lobectomy and lung cancer: 1
- low lobectomy and lymph node: 1
- lung adenocarcinoma and lymph node: 1, 2, 3, 4, 5, 6, 7
- lung cancer and lymph node: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57
- lung cancer poor prognosis and lymph node: 1, 2, 3
- lung cancer stage and lymph node: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- lung cancer therapy and lymph node: 1, 2, 3
- lung function and lymph node: 1, 2, 3, 4, 5, 6
- lung nodule and lymph node: 1, 2, 3, 4, 5
Co phrase search for related documents, hyperlinks ordered by date