Author: dos Reis Neto, Edgard Torres; Kakehasi, Adriana Maria; de Medeiros Pinheiro, Marcelo; Ferreira, Gilda Aparecida; Marques, Cláudia Diniz Lopes; da Mota, Licia Maria Henrique; dos Santos Paiva, Eduardo; Pileggi, Gecilmara Cristina Salviato; Sato, EmÃlia Inoue; Reis, Ana Paula Monteiro Gomides; Xavier, Ricardo Machado; Provenza, José Roberto
Title: Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases Cord-id: 3k48ci7b Document date: 2020_6_9
ID: 3k48ci7b
Snippet: Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention because of the ongoing COVID-19 pandemic. Rheumatologists have been using antimalarials to manage patients with chronic immune-mediated inflammatory rheumatic diseases for decades. It is an appropriate time to review their immunomodulatory and anti-inflammatory mechanisms impact on disease activity and survival of systemic lu
Document: Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention because of the ongoing COVID-19 pandemic. Rheumatologists have been using antimalarials to manage patients with chronic immune-mediated inflammatory rheumatic diseases for decades. It is an appropriate time to review their immunomodulatory and anti-inflammatory mechanisms impact on disease activity and survival of systemic lupus erythematosus patient, including antiplatelet effect, metabolic and lipid benefits. We also discuss possible adverse effects, adding a practical and comprehensive approach to monitoring rheumatic patients during treatment with these drugs.
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