[Follow-up results of 117 discharged patients with coronavirus disease 2019 in Wuhan Mobile Cabin Hospital].

Zheng, Yanlei; Hu, Ronghua; Zhang, Li; Li, Shi

OBJECTIVE To follow up the cured and discharged patients with coronavirus disease 2019 (COVID-19) from Wuhan Mobile Cabin Hospital and investigate their epidemiological and clinical characteristics as well as 2019 novel coronavirus (2019-nCoV) nucleic acid test results, so as to provide evidence for epidemic prevention and control. METHODS The clinical data including epidemiology, clinical symptoms, laboratory and imaging data of 117 patients diagnosed with COVID-19 who were admitted to Wuhan Hongshan Mobile Cabin Hospital from February 6 to March 10, 2020 were collected by telephone follow-up and analyzed, so as to provide evidence for the prevention and treatment of COVID-19. RESULTS Among the 117 COVID-19 patients who met the discharge criteria, there were 49 males and 68 females with an average age of (49.00±11.88) years old, and the average length of hospital stay was (17±6) days. Among them, 91 patients had no obvious symptoms after discharge, and the proportion of asymptomatic patients was 77.78%. A small number of patients had clinical symptoms such as chest distress, palpation and asthma, etc. after discharge. After discharge, 7 patients had chest distress symptom, 5 cases had sore throat and palpitate symptom, 4 patients still had cough, asthma and chest pain existed in 3 cases for each, and headache, diarrhea, difficulty in breathing existed in 1 case for each. The 2019-nCoV nucleic acid results of 7 discharged patients were positive, with a re-positive rate of about 5.98%. The nucleic acid positive result occurred after 10-19 days in meeting the discharge standard. Most of the patients did not receive chest CT scan after discharge, but 24 cases of the patients received chest CT scan during follow-up showed normal manifestations, and the lesions of 6 patients were all almost absorbed or normal. CONCLUSIONS Some patients with COVID-19 in Wuhan Mobile Cabin Hospital who were re-positive with 2019-nCoV nucleic acid after discharge did not cause further transmission. Moreover, the patients with re-positive nucleic acid results were not significantly correlated with their length of hospital stay and the presence of clinical symptoms after discharge as well as CT findings. It is recommended to detect feces or other specimens in discharged patients, and to strengthen the regular monitoring and follow-up of discharged patients.